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Source document· February 25, 2026

TransMedics outlines 20–25% 2026 revenue growth target while advancing OCS programs and European expansion

View original at seekingalpha.com
TransMedics outlines 20–25% 2026 revenue growth target while advancing OCS programs and European expansion Earnings Call Insights: TransMedics Group, Inc…
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  • By organ, liver contributed $127 million, heart $26 million and lung $2 million in Q4

    80% confidence
  • U.S. transplant revenue grew approximately 11% sequentially to $155 million in Q4 2025

    80% confidence
  • OCS Heart comprised 18% of heart transplants in 2025, up from 17% in 2024

    80% confidence
  • Total revenue for Q4 was approximately $161 million with U.S. transplant revenue of approximately $155 million, up 33% year-over-year and 11% sequentially

    80% confidence
  • Q4 2025 total revenue was approximately $161 million, with U.S. transplant revenue of approximately $155 million, up 33% year-over-year and 11% sequentially

    80% confidence
  • TransMedics is not seeing competitive dynamics impacting ability to execute in 2026 and beyond

    80% confidence
  • The makers of styrofoam box competitor are refusing to randomize their technology against OCS in ENHANCE Part B

    80% confidence
  • OCS Liver reached 36% of U.S. liver transplant volume in 2025, up from 26% in 2024

    80% confidence
  • 2026 operating margins expected to be up to approximately 250 basis points below 2025 full year levels, primarily reflecting timing and scale of investments

    80% confidence
  • Almost 50% of incremental investment in 2026 is driven by three elements that are transitory by nature

    80% confidence
  • TransMedics delivered an operating profit of approximately $21.3 million in Q4, representing approximately 13.2% of total revenue

    80% confidence
  • Total revenue for Q4 2025 was $160.8 million, representing approximately 32% year-over-year growth and approximately 12% sequential growth

    80% confidence
  • Total revenue for Q4 was approximately $161 million with U.S. transplant revenue at approximately $155 million, up 33% year-over-year and 11% sequentially

    80% confidence
  • The makers of the styrofoam box technology are refusing to randomize their technology against TransMedics in ENHANCE Part B trial

    80% confidence
  • TransMedics achieved its best operational performance to date in Q4 2025 despite external challenges designed to distract and disrupt growth

    80% confidence
  • Most lung centers were waiting to see FDA approval before launching into DENOVO program

    80% confidence
  • Liver market share gains are pure TransMedics execution excellence, period, full stop

    80% confidence
  • Upcoming registry publication will demonstrate unequivocal statistical superiority in the most important outcomes after liver transplantation

    80% confidence
  • TransMedics delivered an operating profit of approximately $21.3 million in Q4, representing approximately 13.2% of total revenue for fourth quarter while making substantial investments to fuel growth

    80% confidence
  • Most lung centers were waiting to see FDA approval to start launching into DENOVO program

    80% confidence
  • Liver market share gains represent pure TransMedics execution excellence

    80% confidence
  • Almost 50% of incremental 2026 investment is driven by three transitory elements

    80% confidence
  • Operating margins expected to approach 30% by 2028

    80% confidence
  • Operating margins expected to be up to approximately 250 basis points below 2025 full year levels in 2026, primarily reflecting timing and scale of investments

    80% confidence
  • OCS was responsible for 5,139 U.S. transplants in 2025, up from 3,735 in 2024

    80% confidence
  • Operating profit of approximately $21.3 million in Q4 represented approximately 13.2% of total revenue

    80% confidence
  • NOP Connect 2.0 is showing efficiency in management and billing, though in early stages

    80% confidence
  • Almost 50% of the incremental investment in 2026 is driven by really 3 elements and those, by nature, are transitory

    80% confidence
  • TransMedics is laser-focused on ensuring successful execution of initiatives throughout 2026

    80% confidence
  • TransMedics was prepared and expected ENHANCE Part B trial challenges, and will execute Part B hoping for significant success

    80% confidence
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AI Capital Keeps Flowing as Enterprise Adoption and Government Contracts Validate the Bet
A late-August surge of nine-figure funding rounds (Socure, Stability AI, Generalist AI, Gatik, Regent Craft, Emerald AI, Owner) shows venture capital still pouring into AI infrastructure, identity/fintech, and autonomy, even as public-market sentiment stays jumpy — Palantir's stock fell 6% the same week it landed the Army's TITAN contract. UiPath's raised guidance and strong Q2 results, alongside efficiency breakthroughs like Multiverse Computing's model compression, point to real enterprise monetization catching up to the funding hype.
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EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
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JPMorgan Chase & Co.
Both facts record the same attribute (net_income) for JPMorgan Chase & Co. in the identical fiscal period (Q1 2026) and observation date (2026-03-31), but report values that differ by approximately 1 billion times: $16,494,000,000 vs $16.49. These cannot both be true simultaneously. The discrepancy suggests either a unit mismatch (e.g., one is total net income, the other earnings per share mislabeled as net_income), a decimal point error, or data entry corruption. For the same entity, attribute, and time period, only one value can be correct.
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