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Source document· November 29, 2025

10 truths about the stock market

View original at finance.yahoo.com
10 truths about the stock market This post was originally published on TKer.co on October 15, 2021. The stock market can be an intimidating place: it’s real money on the line, there’s an overwhelming amount of information to follow, and people have lost fortunes in it very quickly…
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  • A stock can only go down by 100%, but there's no limit to how many times that value can multiply going up

    80% confidence
  • The S&P 500 has usually generated positive annual returns with an average drawdown of 14% during those years

    80% confidence
  • The stock market has an upward bias. There are way more people who want things to be better, not worse. And that demand incentivizes entrepreneurs and businesses to develop better goods and services

    80% confidence
  • Over the long term, the stock market news will be good

    80% confidence
  • The most commonly cited risks are the ones that are already priced into the markets. It's the risks no one is talking about or few are concerned about that'll rock markets when they come to surface

    80% confidence
  • Any long term move in a stock can ultimately be explained by the underlying company's earnings, expectations for earnings, and uncertainty about those expectations for earnings

    80% confidence
  • The stock market generates about 10% annual returns on average

    80% confidence
  • While valuation methods may tell you something about long-term returns, most tell you almost nothing about where prices are headed in the next 12 months

    80% confidence
  • Made a remarkably prescient market observation in 1994

    80% confidence
  • The economy reflects all of the business being conducted in the U.S. while the market reflects the performance of the biggest companies — which typically have access to lower-cost financing and have the scale to source goods and labor more cheaply

    80% confidence
  • Since 1926, there's never been a 20-year period where the stock market didn't generate a positive return

    80% confidence
  • It's the addition of new and unexpected companies that have been driving much of the S&P 500's returns over the past decade

    80% confidence
  • In the 20th century, the United States endured two world wars and other traumatic and expensive military conflicts; the Depression; a dozen or so recessions and financial panics; oil shocks; a flu epidemic; and the resignation of a disgraced president. Yet the Dow rose from 66 to 11,497

    80% confidence
What we know · the intelligence behind this page
Live from the substrate
What we're seeing
ESMO 2026 Oncology Data Wave Builds Toward Ivonescimab PDUFA, While Micro-Cap Biotech Exits the Market
Late October 2026 is a dense catalyst window led by ESMO 2026. Daiichi Sankyo's DXd antibody-drug conjugate (ADC) programs (DESTINY-Lung04, DESTINY-Breast11, REJOICE-Ovarian01/02, TUXEDO-3), Guardant's 25 abstracts and the PACE-LUNG ctDNA trial all report there. These feed into the FDA's 14 November 2026 PDUFA date for ivonescimab. Large and mid-cap developers with late-stage data and commercial launches (ZEGFROVY, ANKTIVA, MIUDELLA, lorundrostat, duvakitug) are drawing capital and attention. Spago Nanomedical's board decision to seek a Nasdaq First North delisting (EGM 19 November, application 25 January 2027) shows the capital squeeze on early-stage, single-asset names (Tumorad is Phase I).
Our read on the data ›
Signals we're tracking
EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Patterns we're watching ›
Where sources disagree
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
We flag conflicts openly ›
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