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News articleYahoo Finance· April 16, 2026

Janux Therapeutics Announces First Participant Dosed in Phase 1 Study of JANX014

View original at finance.yahoo.com
Janux Therapeutics Announces First Participant Dosed in Phase 1 Study of JANX014 -JANX014 expands Janux’s PSMA tumor-activated T cell engager portfolio -JANX007 is the Company’s lead prostate cancer program and primary development priority -JANX013, a PSMA-TRACIr CD28 co-stimulatory program, planned to enter the clinic…
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  • JANX007 has shown a favorable safety profile with no Grade 3 cytokine release syndrome observed at clinically relevant dose levels using the current CRS mitigation strategy

    60% confidence

  • We are building a prostate cancer portfolio designed to address patients across multiple stages of disease, including both single and combination approaches

    60% confidence

  • JANX007 remains our lead prostate program, and we believe it has established a strong clinical foundation for PSMA-directed TRACTr therapy

    60% confidence

  • Janux's tumor-activated technology allows us to evaluate multiple molecular designs against the same validated target

    60% confidence

  • Early clinical data from JANX007 have demonstrated what Janux believes is potentially a best-in-class clinical profile in mCRPC

    60% confidence

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