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News articleYahoo Finance· May 15, 2026

Rigel Pharmaceuticals Inks Breast Cancer Drug Deal With Arvinas, Pfizer

View original at finance.yahoo.com
Rigel Pharmaceuticals Inks Breast Cancer Drug Deal With Arvinas, Pfizer Benzinga and Yahoo Finance LLC may earn commission or revenue on some items through the links below…
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  • Median PFS was 5.0 months in the vepdegestrant arm and 2.1 months in the fulvestrant arm in VERITAC-2.

    60% confidence
  • Overall survival data was immature at the time of the PFS analysis, with 16% of deaths recorded in the population.

    60% confidence
  • The licensing agreement allows Rigel to launch VEPPANU in the U.S. and pursue global rights, potentially leading to significant revenue growth.

    60% confidence
  • Rigel will contribute up to $40 million towards VEPPANU development over the next four years under the licensing agreement.

    60% confidence
  • The FDA approval of vepdegestrant was based on data showing the drug reduced the risk of disease progression or death by 43% compared to fulvestrant.

    60% confidence
  • In the Phase 3 VERITAC-2 trial, vepdegestrant was generally well tolerated and demonstrated a statistically significant and clinically meaningful improvement in progression-free survival compared to fulvestrant.

    60% confidence

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AI-Driven Drug Development Meets Biotech Deal-Making and Regulatory Catalysts
AI-designed therapeutics (Insilico's rentosertib showing biological-age reductions) are moving into the clinical mainstream. Large-cap biotech is simultaneously reallocating capital through M&A (Lilly–Merida, $2.9B) and government funding (BARDA–Basilea), while trial failures (ziltivekimab, a 9.4% Novo Nordisk share drop) and upcoming FDA catalysts (the ivonescimab PDUFA on 2026-11-14) drive volatility. The wider AI regulatory and legal climate (Tesla Cybercab probe, xAI's Minnesota loss, OpenAI suits) is tightening, though QAIAx's micro-cap trial claims are speculative and weakly connected.
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ING Group
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